The Science Behind the Imeka 3D Animation

In this science animation for INmune Bio and Imeka, we explain how white matter degeneration is a key early event in neurodegenerative diseases. Axons, insulated by myelin, form white matter tracts that allow efficient neuron communication. However, immune cells can trigger neurodegeneration, stripping myelin, breaking down synapses, and ultimately causing irreversible neuron death.

INmune Bio is developing XPro1595, a therapy designed to treat white matter pathology by reducing neuroinflammation, promoting remyelination, and restoring axonal function. Imeka’s cutting-edge MRI technology enables precise measurement of white matter integrity, tracking changes in axons, myelin, and inflammation. Early clinical data suggest that XPro1595 improves white matter health in Alzheimer’s patients, offering hope for more effective neurodegenerative disease treatments.

Learn more at inmunebio.com and imeka.ca.

The Challenge: How Do You Animate What Can’t Be Seen?

When Imeka and INmune Bio came to us, the question was straightforward, but the visuals weren’t. They needed a 3D animation that explained how white matter is damaged and how their therapy and imaging technology could track recovery. But how do you show something as subtle and internal as neuroinflammation and axonal damage without falling into generic “brain drug” visuals?

We knew this had to be more than just good-looking—it had to be scientifically precise, emotionally resonant, and strategically useful.

3D view of axons and myelin sheaths in the brain – showing neurostructure central to the Imeka 3D animation for neurodegenerative research.

This 3D scene from the Imeka animation shows the structure of axons and their insulating myelin sheaths—key to neuron function and communication.

Our Process: Bringing Science to Life in the Imeka 3D Animation

We started by asking the hard questions:

  • What exactly does Imeka measure in the brain?

  • How does white matter damage look in a visual metaphor?

  • How can we make the benefits of XPro1595 feel tangible?

The answers shaped every frame. We created a visual world inspired by diffusion MRI—showing axons, synapses, and myelin damage in a style that reflected Imeka’s clean, high-tech brand. Throughout, we stayed close to the data but focused on clarity over detail-dumping.

This wasn’t a generic explainer—it was a custom-built Imeka 3D animation designed to help them stand out.

3D illustration of oligodendrocytes, astrocytes, and microglia interacting with axons in white matter – from the Imeka 3D animation.

This close-up 3D scene from the Imeka animation shows glial cells—astrocytes, microglia, and oligodendrocytes—affecting axons in white matter.

A Pivotal Question: Why Does This Matter?

Midway through the project, the client challenged us:

“It’s scientifically accurate, but can we also show why this matters for clinical decisions?”

That insight helped us refocus the ending. Instead of finishing on biology alone, we added a moment where data visualization supports brighter go/no-go decisions in clinical trials. That’s the core of Imeka’s value – and now it’s the closing message of the animation.

The Outcome: A Video That Connects Science and Strategy

The final Imeka 3D animation:

  • Explains white matter science clearly and visually

  • Shows the combined impact of imaging + therapy

  • Helps the client spark interest with pharma and investor audiences

It’s become a trusted piece of communication – for both scientific credibility and business development.

Need a science animation that does more than just explain?
Let’s talk about how we can turn your research into a powerful story.