Explaining Stroke Treatment with a 3D Mode of Action Video

In this 3D Mode of Action video for Basking Biosciences, we explain how von Willebrand factor (vWF) plays a central role in clot formation, stabilization, and expansion.

When blood vessels are damaged, vWF binds to platelets and collagen, forming a sticky lattice that amplifies clot growth.
Basking Biosciences is developing BB-31, an RNA aptamer that binds to vWF, disrupts its activity, and gradually dissolves the clot. It works from the outer shell inward—destabilizing the clot’s structure and restoring blood flow.

Currently in Phase 2 clinical trials, BB-31 represents a potential breakthrough for treating acute ischemic stroke and other thrombotic conditions.


Behind the Scenes: Producing Basking’s 3D Mode of Action Video

Creating the Hero Animation for a Thrombolytic Therapy

Basking Biosciences needed more than just a visual—
they needed a hero animation that captured their entire therapeutic approach in one compelling loop.

Here’s how we brought the 3D Mode of Action video to life—and the key production challenges we solved.


The Request: A Looping 3D Clip for the Homepage

The client wanted to replace a generic stock clip on their homepage with a short, seamless animation showing:

  • Clot formation
  • BB-31’s targeted mechanism
  • The effect on blood flow

It had to loop smoothly, support overlaid text, and stay under 12 MB for fast loading.


Production Challenges in Creating a 3D Mode of Action Video

1. Creating a Seamless Animation Loop

Looping medical animations can feel jarring if not carefully designed. We used advanced frame blending and cross-fading techniques to ensure the last frame matched the first—creating a perfect loop without abrupt transitions.


2. High-Quality Slow Motion Rendering

The client requested a slow-motion effect to better showcase BB-31’s mechanism.
We re-rendered the full scene at a higher frame rate (48 fps), doubling render time but preserving smooth playback without stutter.


3. Web-Optimized File Delivery

To meet the developer’s file size limit, we compressed the video without sacrificing visual clarity. We also advised keeping visual overlays like fades and darkening effects in CSS, not baked into the video, ensuring design flexibility.


4. Maintaining Visual Focus

Callouts were considered to label the drug interaction sites, but we recommended against them for this version. Our goal was a calm, ambient animation that enhanced the page without overwhelming the viewer.


Outcome: A High-Impact 3D Mode of Action Video That Converts

The final clip now loops on Basking’s homepage and supports their messaging across internal pages.
We also delivered high-resolution stills—used in banners and headers—making the video a core part of their brand experience.

The impact was immediate:
Before reading a word, viewers understood what Basking was working on.

That’s the power of a well-executed 3D Mode of Action video.

Let’s discover together how we can simplify your science, too. Contact us now.